منابع مشابه
Bone resorption in parathyroid carcinoma.
To cite: Naderi N, McCurdy MT, Reed RM. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013203396 DESCRIPTION A man in his 30s with a history of end-stage renal disease (ESRD) and metastatic parathyroid carcinoma presented to the hospital with severe shortness of breath, hypercalcaemia and diffuse bone pain. Chest radiograph (figure 1A) demonstrated profound demi...
متن کاملA role for interleukin-6 in parathyroid hormone-induced bone resorption in vivo.
Parathyroid hormone (PTH) exerts its regulatory effects on calcium homeostasis in part by stimulating the release of calcium from the skeleton. PTH stimulates bone resorption indirectly, by inducing the production by stromal/osteoblastic cells of paracrine agents which recruit and activate the bone-resorbing cell, the osteoclast. The identity of the stromal cell/osteoblast-derived paracrine fac...
متن کاملAn analysis of the role of serum in parathyroid hormone-induced bone resorption in tissue culture.
THE stimulation of bone resorption by parathyroid hormone can be quantitated in tissue cultures of embryonic bone [20], using paired limb bones from a single embryo in which radioactive calcium (45Ca) has previously been incorporated. The ratio of 45Ca release from the parathyroid hormonetreated bones to that from the control bones is a sensitive measure of parathyroid effect. This technique ha...
متن کاملParathyroid hormone-related protein-(107-139) inhibits bone resorption in vivo.
PTH-related protein-(107-139) [PTHrP-(107-139)] has been reported previously to be a potent inhibitor of osteoclast activity. However, this finding has not been reproduced in other in vitro models. We have now examined the effects of this peptide in an in vivo model, employing intact adult mice. Four groups of eight male mice were given injections of either vehicle or one of three doses of PTHr...
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ژورنال
عنوان ژورنال: Case Reports
سال: 2014
ISSN: 1757-790X
DOI: 10.1136/bcr-2013-203396